Publications [1] Adam, W.; Fröhlich, L.; Nau, W. M.; Wirz, J. Effects of Symmetrical Diaryl Substitution on Intersystem Crossing in 1,3-Cyclopentanediyl Triplet Biradicals. J. Am. Chem. Soc. 1993, 115, 9824-9825. [2] Adam, W.; Fröhlich, L.; Nau, W. M.; Korth, H. G.; Sustmann, R. Substituenteneinflüsse auf die Nullfeldparameter von lokalisierten Triplett-1,3-Cyclopentandiyl-Diradikalen. Angew. Chem. 1993, 105, 1383-1384. [3] Linker, T.; Fröhlich, L. Regio- und diastereoselektive Photooxygenierung chiraler 2,5-Cyclohexadien-1-carbonsäuren. Angew. Chem. 1994, 106, 2064-2066. [4] Linker, T.; Fröhlich, L. Substituent Effects in the Highly Regioselective and Diastereoselective Ene Reaction of Singlet Oxygen with Chiral Cyclohexadienes. J. Am. Chem. Soc. 1995, 117, 2694-2697. [5] Peters, K.; Peters, E. M.; Linker, T.; Fröhlich, L. Crystal structure of 1-hydroperoxy-3-isopropyl-2-methylenecyclohex-4-ene-3-carboxylic acid, C11H16O4. Zeitschrift für Kristallographie 1996, 211, 359. [6] Peters, K.; Peters, E. M.; Linker, T.; Fröhlich, L. Crystal structure of 1,2-dimethyl-2,5-cyclohexadiene-1-carboxylic acid, C9H12O2. Zeitschrift für Kristallographie 1996, 211, 361. [7] Bömmel, H. M.; Reif, A.; Fröhlich, L. G.; Frey, A.; Hofmann, H.; Marecak, D. M.; Groehn, V.; Kotsonis, P.; La, M.; Köster, S.; Meinecke, M.; Bernhardt, M.; Weeger, M.; Ghisla, S.; Prestwich, G. D.; Pfleiderer, W.; Schmidt, H. H. H. W. Anti-pterins as Tools to Characterize the Function of Tetrahydrobiopterin in NO Synthase. J. Biol. Chem. 1998, 273, 33142-33149. [8] Kotsonis, P.; Frey, A.; Fröhlich, L. G.; Hofmann, H.; Reif, A.; Wink, D. A.; Feelisch, M.; Schmidt, H. H. H. W. Autoinhibition of Nitric Oxide Synthase – Distinct Effects of Reactive Nitrogen and Oxygen Species on Enzyme Activity and Quatenary Structure. Biochem. J. 1999, 340, 745- 752. [9] Reif, A.; Fröhlich, L. G.; Kotsonis, P.; Frey, A.; Bömmel, H. M.; Wink, D. A.; Pfleiderer, W.; Schmidt, H. H. H. W. Tetrahydrobiopterin Inhibits Monomerization and is Consumed During Catalysis in Neuronal NO Synthase. J. Biol. Chem. 1999, 274, 24921-24929. [10] Fröhlich, L. G.; Kotsonis, P.; Traub, H.; Taghavi-Moghadam, S.; Al-Masoudi, N.; Hofmann, H.; Strobel, H.; Matter, H.; Pfleiderer, W.; Schmidt, H. H. H. W. Inhibition of Neuronal Nitric Oxide Synthase by 4-Amino Pteridine Derivatives: Structure-Activity Relationship of Antagonists of (6R)- 5,6,7,8-Tetrahydrobiopterin Cofactor. J. Med. Chem. 1999, 42, 4108-4121. [11] Butt, E.; Bernhardt, M.; Smolenski, A.; Kotsonis, P.; Fröhlich, L. G.; Sickmann, A.; Meyer, H. E.; Lohmann, S. M.; Schmidt, H. H. H. W. Endothelial Nitric Oxide Synthase (Type III) is Activated and Becomes Calcium-Independent upon Phosphorylation by Cyclic Nucleotide- dependent Protein Kinases. J. Biol. Chem. 2000, 275, 5179-5187. [12] Kotsonis, P.; Fröhlich, L. G.; Shutenko, Z. V.; Horejsi, R.; Pfleiderer, W.; Schmidt, H. H. H. W. Allosteric Regulation of Neuronal Nitric-Oxide Synthase by Tetrahydrobiopterin and Suppression of Auto-damaging Superoxide. Biochem. J. 2000, 346, 767-776. [13] Groehn, V.; Fröhlich, L., Schmidt, H. H. H. W.; Pfleiderer, W. Pteridine-Based Photoaffinity Probes for Nitric Oxide Synthase and Aromatic Amino Acid Hydroxylases. Helv. Chim. Acta 2000, 83, No. 10, 2738-2750. [14] Kotsonis, P.; Fröhlich, L. G.; Raman, C. S.; Li, H.; Berg, M.; Gerwig, R.; Groehn, V.; Kang, Y.; Al-Masoudi, N.; Taghavi-Moghadam, S.; Mohr, D.; Münch, U.; Schnabel, J.; Martasek, P.; Masters, B. S. S.; Strobel, H.; Poulos, T.; Matter, H.; Pfleiderer, W. and Schmidt, H. H. H. W. Structural basis for Pterin antagonism in nitric oxide synthase: Development of novel 4-Oxo Pteridine antagonists of (6R)-5,6,7,8-tetrahydrobiopterin. J. Biol. Chem. 2001, 276, 49133-49141. [15] Houbertz, R.; Fröhlich, L.; Schulz, J.; Popall, M. Inorganic-organic Hybrid Materials (ORMOCERÒs) for Multilayer Technology – Passivation and Dielectric Behavior. Mat. Res. Soc. Symp. Proc. 2001, Vol. 665, 321-326. [16] Matter, H.; Kotsonis, P.; Klingler, O.; Strobel, H.; Fröhlich, L. G.; Frey, A.; Pfleiderer, W.; Schmidt, H. H. H. W. Structural Requirements for Inhibition of the Neuronal Nitric Oxide Synthase (NOS-I): 3D-QSAR Analysis of 4-Oxo and 4-Amino-Pteridine-Based Inhibitors. J. Med. Chem. 2002, 45, 2923-2941. [17] Fröhlich, L.; Houbertz, R.; Jacob, S.; Popall, M.; Müller-Fiedler, R.; Graf, J.; Munk, M.; von Zychlinski, H. Inorganic-Organic Hybrid Polymers as Photo-Patternable Dielectrics for Multilayer Microwave Circuits. Mat. Res. Soc. Symp. Proc. 2002, Vol. 726, 349-354. [18] Streppel, U.; Dannberg, P.; Wächter, C.; Bräuer, A.; Fröhlich, L.; Houbertz, R.; Popall, M. New wafer-scale fabrication method for stacked optical waveguide interconnects and 3 D micro-optic structures using photoresponsive (inorganic-organic hybrid-) polymers. Opt. Mat. 2002, 21/1-3, 479-487. [19] Serbin, J.; Egbert, A.; Ostendorf, B.; Chichkov, B. N.; Houbertz, R.; Domann, G.; Schulz, J.; Cronauer, C.; Fröhlich, L.; Popall, M. Femtosecond laser-induced two-photon polymerization of inorganic organic hybrid materials  for applications in photonics. Opt. Lett. 2003, 28/5, 301-303. [20] Johansson, C.; Uhlig, S.; Tageman, O.; Alping, A.; Haglund, J.; Robertsson, M.; Popall, M.; Fröhlich, L. Microwave Circuits in Multilayer Inorganic-Organic Polymer Thin Film Technology on Laminate Substrates. IEEE Transactions on Advanced Packaging, 2003, Vol. 26, 81-89. [21] Houbertz, R.; Schulz, J.; Fröhlich, L.; Domann, G.; Popall, M. Inorganic-organic hybrid materials for polymer electronic applications. Mat. Res. Soc. Symp. Proc. 2003, Vol. 769, 239-244. [22] Houbertz, R.; Schulz, J.; Fröhlich, L.; Domann, G.; Popall, M. Inorganic-organic hybrid materials for real 3-D sub-µm lithography. Mat. Res. Soc. Symp. Proc. 2003, Vol. 780, 175-180. [23] Houbertz, R.; Domann, G.; Cronauer, C.; Schmitt, A.; Martin, H.; Park, J.-U.; Fröhlich, L.; Buestrich, R.; Popall, M.; Streppel, U.; Dannberg, P.; Wächter, C.; Bräuer, A. Inorganic-organic hybrid materials for application in optical devices. Thin Solid Films, 2003, 442, 194-200. [24] Houbertz, R.; Fröhlich, L.; Popall, M.; Streppel, U.; Dannberg, P.; Bräuer, A.; Serbin, J.; Chichkov, B. Inorganic-Organic Hybrid Polymers for Information Technology: from Planar Technology to 3D Nanostructures. Advanced Engineering Materials, 2003, 5 No. 8, 551-555. [25] Fröhlich, L.; Linker, T. Simple and Diastereoselective Synthesis of an A-Ring Precursor of Dihydroxyvitamin D3 (Calcitriol) by Photooxygenation. Synlett, 2004, 15, 2725-2727. [26] Houbertz, R.; Domann, G.; Schulz, J.; Olsowski, B.; Fröhlich, L.; Kim, W.S. Impact of photoinitiators on the polymerization and the optical properties of inorganic-organic hybrid polymers. Applied Physics Letters, 2004, 84/7, 1105-1107. [27] Matter, H.; Kumar, H. S. A.; Federov, R.; Frey, A.; Kotsonis, P.; Hartmann, E.; Fröhlich, L. G.; Reif, A.; Pfleiderer, W.; Scheurer, P.; Ghosh, D. K.; Schlichting, I.; Schmidt, H. H. H. W. Structural Analysis of Isoform-Specific Inhibitors Targeting the Tetrahydrobiopterin Binding Site of Human Nitric Oxide Synthases. J. Med. Chem., 2005, 48, 4783-4792. [28] Uhlig, S.; Domann, G.; Houbertz, R.; Fröhlich, L.; Schröder, H.; Krissler, J.;  Lang, G.; Robertsson, M. Preventing of dewetting effects for inorganic-organic hybrid polymers applied in sequentially buildup (SBU) technology without surface pretreatments. IEEE Transactions on Electronics Packaging Manufacturing, 2006, 297-307. [29] Uhlig, S.; Fröhlich, L.; Chen, M.; Arndt-Staufenbiel, N.; Schröder, H.; Houbertz, R.; Popall, M.; Robertsson, M. Polymer optical interconnects – a scalable large-area panel processing approach. IEEE Transactions on Advanced Packaging, 2006, 29/1, 158-170.